Depression and cardiovascular disease are very common, and they often coexist. Major depression is considered a primary and secondary risk factor for hypertension, coronary artery disease, myocardial Infarction, and congestive heart failure. Nevertheless, depressive episodes, minor depression, dysthymia, and several subsyndromal forms of depression, currently included in the realm of ‘‘mood spectrum disorders,’’ might have a role in the etiology of these cardiovascular diseases. Despite the exact pathways underlying the interplay between depressive spectrum disorders and cardiovascular disease have yet to be elucidated, the existence of a bidirectional relationship has been postulated. The aim of this manuscript is either to reconsider the clinical evidences of the relationship between depressive spectrum disorders and cardiovascular disease or the hypothesis of a common psychoorganic etiological background by a systematic search from MEDLINE and PsychINFO articles with participants over 18 years.

Spectrum of Depressive Disorders and Cardiovascular Diseases: Clinical and Psychobiological Evidences of a Bidirectional Relationship

Palagini L
Primo
;
2012

Abstract

Depression and cardiovascular disease are very common, and they often coexist. Major depression is considered a primary and secondary risk factor for hypertension, coronary artery disease, myocardial Infarction, and congestive heart failure. Nevertheless, depressive episodes, minor depression, dysthymia, and several subsyndromal forms of depression, currently included in the realm of ‘‘mood spectrum disorders,’’ might have a role in the etiology of these cardiovascular diseases. Despite the exact pathways underlying the interplay between depressive spectrum disorders and cardiovascular disease have yet to be elucidated, the existence of a bidirectional relationship has been postulated. The aim of this manuscript is either to reconsider the clinical evidences of the relationship between depressive spectrum disorders and cardiovascular disease or the hypothesis of a common psychoorganic etiological background by a systematic search from MEDLINE and PsychINFO articles with participants over 18 years.
2012
Palagini, L; Bruno, Rm; Guazzelli, M; Taddei, S; Gemignani, A; Ghiadoni, L
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2517490
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact