Oral manifestations in children with acute lymphoblastic Leukemia

Leukaemia, a form ofabnormal and atypical proliferation of undeveloped white cells, is the most common form ofmalignant neoplasia in childhood. The different forms of Ieukaemia are characterized by a high incidence of ora! complications. Moreover, oral injuries may be the first predictor of the illness helping to diagnose Ieukaemia, even if the histologic examination of the marrow is required for a certain diagnosis. Actually the early diagnosis oforal injuries is really important for prevention and treatment of the complications that may anse during the therapy: a better prognosis and Iower morbidity and mortality for this illness ensue. Furthermore, even after remission, the young patient increasingly needs a constant monitoring of the oral cavity because of the delayed effects of the illness and the therapy. Therefore a dental treatment programme for paediatric haemato-oncological patients is very important to improve quality of life of Ieukemic children.