The COVID-19 clinical presentation is extremely heterogenous and, in older people, it is influenced not simply by chronologic age but also by common geriatric syndromes, such as multimorbidity, motor disability, and frailty. Consequently, although typical respiratory symptoms remain the most frequent clinical presentation of COVID-19 in all age classes, in older patients, atypical symptoms (including but not limited to delirium and hyporexia) are more common than in middle-aged adults and have been associated with adverse outcomes. Moreover, some studies described the tendency of COVID-19 presenting symptoms to aggregate in clusters, and this approach seems to better capture the complexity of COVID-19 disease. The prognostic value of COVID-19 symptom clusters, however, is currently poorly investigated, especially in the older population.

Clinical Features of SARS-CoV-2 Infection in Older Adults

Remelli F.
Primo
;
Volpato S.;Trevisan C.
Ultimo
2022

Abstract

The COVID-19 clinical presentation is extremely heterogenous and, in older people, it is influenced not simply by chronologic age but also by common geriatric syndromes, such as multimorbidity, motor disability, and frailty. Consequently, although typical respiratory symptoms remain the most frequent clinical presentation of COVID-19 in all age classes, in older patients, atypical symptoms (including but not limited to delirium and hyporexia) are more common than in middle-aged adults and have been associated with adverse outcomes. Moreover, some studies described the tendency of COVID-19 presenting symptoms to aggregate in clusters, and this approach seems to better capture the complexity of COVID-19 disease. The prognostic value of COVID-19 symptom clusters, however, is currently poorly investigated, especially in the older population.
2022
Remelli, F.; Volpato, S.; Trevisan, C.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2494480
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