A specific and sensitive indirect ELISA method with two linear synthetic peptides/mimotopes, mimicking the MCPyV VP1/VP2 antigens to detect circulating IgGs against MCPyV immunogenic antigens in AD patients was developed and validate. Two linear synthetic peptides, named MCPyV VP1 S and VP2 F (S/F peptides), were designed and employed in indirect ELISA as mimotopes to detect anti-MCPyV IgGs.
Immunoassay for the detection of antibodies against Merkel cell polyomavirus
Martini, Fernanda
;Rotondo, John Charles;Mazzoni, Elisa;Torreggiani, Elena;Mazziotta, Chiara;Lanzillotti, Carmen;Tognon, Mauro
2022
Abstract
A specific and sensitive indirect ELISA method with two linear synthetic peptides/mimotopes, mimicking the MCPyV VP1/VP2 antigens to detect circulating IgGs against MCPyV immunogenic antigens in AD patients was developed and validate. Two linear synthetic peptides, named MCPyV VP1 S and VP2 F (S/F peptides), were designed and employed in indirect ELISA as mimotopes to detect anti-MCPyV IgGs.File in questo prodotto:
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