Impact of coinfection with SARS-CoV-2 on HIV replication in CNS is unknown. SARS-CoV-2 could alter the BBB permeability and cause a CNS HIV escape. Few symptoms during COVID-19 suggest a contained inflammatory response in CNS/plasma. Poor immunological recovery might contribute to avoid immune-pathogenetic processes. We report twocases of HIV positive patients with COVID-19 infection and a recent diagnosis of opportunistic infections of central nervous system (CNS). We investigated the potential impact of coinfection with SARS-CoV-2 on HIV replication in CNS.
SARS-CoV-2 infection does not induce HIV viral escape in Central Nervous System: a case series
Campioni, P.;
2020
Abstract
Impact of coinfection with SARS-CoV-2 on HIV replication in CNS is unknown. SARS-CoV-2 could alter the BBB permeability and cause a CNS HIV escape. Few symptoms during COVID-19 suggest a contained inflammatory response in CNS/plasma. Poor immunological recovery might contribute to avoid immune-pathogenetic processes. We report twocases of HIV positive patients with COVID-19 infection and a recent diagnosis of opportunistic infections of central nervous system (CNS). We investigated the potential impact of coinfection with SARS-CoV-2 on HIV replication in CNS.File in questo prodotto:
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