Cardiovascular disease (CVD) is the principal cause of death in women. Walking speed (WS) is strongly related with mortality and CVD. The rate of all-cause hospitalization or death was assessed in 290 female outpatients with CVD after participation in a cardiac rehabilitation/secondary prevention program (CR/SP) and associated with the WS maintained during a moderate 1 km treadmill-walk. Three-year mortality rates were 57%, 44%, and 29% for the slow (2.1 +/- 0.4 km/h), moderate (3.1 +/- 0.3 km/h), and fast (4.3 +/- 0.6 km/h) walkers, respectively, with adjusted hazard ratios (HRs) of 0.78 (p =0.24) and 0.55 (p =0.03) for moderate and fast walkers compared to the slow walkers. In addition, hospitalization or death was examined four to six years after enrollment as a function of the change in the WS of 176 patients re-assessed during the third year after baseline. The rates of hospitalization or death were higher across tertiles of reduced WS, with 35%, 50%, and 53% for the high (1.5 +/- 0.3 km/h), intermediate (0.7 +/- 0.2 km/h), and low tertiles (0.2 +/- 0.2 km/h). Adjusted HRs were 0.79 (p =0.38) for the intermediate and 0.47 (p =0.02) for the high tertile compared to the low improvement tertile. Improved walking speed was associated with a graded decrease in hospitalization or death from any cause in women undergoing CR/SP.

Impact of Improvement in Walking Speed on Hospitalization and Mortality in Females with Cardiovascular Disease

Giovanni Grazzi
Primo
;
Gianni Mazzoni;Lorenzo Caruso;Biagio Sassone;Giovanni Pasanisi;Franco Guerzoni;Matteo Pizzolato;Valentina Zerbini;Michele Franchi;Sabrina Masotti;Simona Mandini;Andrea Raisi
;
Giorgio Chiaranda
2020

Abstract

Cardiovascular disease (CVD) is the principal cause of death in women. Walking speed (WS) is strongly related with mortality and CVD. The rate of all-cause hospitalization or death was assessed in 290 female outpatients with CVD after participation in a cardiac rehabilitation/secondary prevention program (CR/SP) and associated with the WS maintained during a moderate 1 km treadmill-walk. Three-year mortality rates were 57%, 44%, and 29% for the slow (2.1 +/- 0.4 km/h), moderate (3.1 +/- 0.3 km/h), and fast (4.3 +/- 0.6 km/h) walkers, respectively, with adjusted hazard ratios (HRs) of 0.78 (p =0.24) and 0.55 (p =0.03) for moderate and fast walkers compared to the slow walkers. In addition, hospitalization or death was examined four to six years after enrollment as a function of the change in the WS of 176 patients re-assessed during the third year after baseline. The rates of hospitalization or death were higher across tertiles of reduced WS, with 35%, 50%, and 53% for the high (1.5 +/- 0.3 km/h), intermediate (0.7 +/- 0.2 km/h), and low tertiles (0.2 +/- 0.2 km/h). Adjusted HRs were 0.79 (p =0.38) for the intermediate and 0.47 (p =0.02) for the high tertile compared to the low improvement tertile. Improved walking speed was associated with a graded decrease in hospitalization or death from any cause in women undergoing CR/SP.
2020
Grazzi, Giovanni; Mazzoni, Gianni; Myers, Jonathan; Caruso, Lorenzo; Sassone, Biagio; Pasanisi, Giovanni; Guerzoni, Franco; Napoli, Nicola; Pizzolato, Matteo; Zerbini, Valentina; Franchi, Michele; Masotti, Sabrina; Mandini, Simona; Raisi, Andrea; Chiaranda, Giorgio
File in questo prodotto:
File Dimensione Formato  
jcm-09-01755.pdf

accesso aperto

Descrizione: versione editoriale
Tipologia: Full text (versione editoriale)
Licenza: Creative commons
Dimensione 530.65 kB
Formato Adobe PDF
530.65 kB Adobe PDF Visualizza/Apri

I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2420195
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 7
  • ???jsp.display-item.citation.isi??? 5
social impact