Coronavirus-HKU1 Pneumonia and Differential Diagnosis with COVID 19

74-year-old female, with fever and dry cough for 5 days, had an epidemiologic link with her sister, who tested positive for SARS-Cov-2. Laboratorial studies revealed elevated C-reactive protein and normal white cell count with neutrophilia. Chest CT obtained at admission showed multiple ground-glass opacities in both upper and left lower lobes, with small pleural effusions. The patient was negative for SARS-CoV-2 on three polymerase chain reaction (PCR) nasopharyngeal swab tests. Serological tests for SARS-CoV-2 were also negative. A subsequent analysis for other respiratory viruses was positive for HKU1-CoV, and follow-up CT performed after 2 weeks of therapy showed almost complete radiological resolution