The application of a novel chromatographic approach to therapeutic peptides bearing basic amino acids in their structure allowed unprecedented resolution of their related impurities (including epimeric isobaric ones), resulting in a superior analytical tool for the evaluation of the quality of these drugs in the market.

Boosting basic-peptide separation through dynamic electrostatic-repulsion reversed-phase (d-ERRP) liquid chromatography

Omar H. Ismail;Martina Catani;Alberto Cavazzini
Penultimo
;
2020

Abstract

The application of a novel chromatographic approach to therapeutic peptides bearing basic amino acids in their structure allowed unprecedented resolution of their related impurities (including epimeric isobaric ones), resulting in a superior analytical tool for the evaluation of the quality of these drugs in the market.
Mazzoccanti, Giulia; Manetto, Simone; Bassan, Michele; Foschini, Alberto; Orlandin, Andrea; Ricci, Antonio; Cabri, Walter; Ismail, Omar H.; Catani, Martina; Cavazzini, Alberto; Gasparrini, Francesco
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2418861
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