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EnglishPenetrating keratoplasty was performed on five pairs of rabbit eyes; one eye of each animal received a donor cornea stored in McCarey-Kaufman (M-K) medium containing gentamicin, and the contralateral eye received a donor cornea stored in M-K medium without gentamicin. At the end of surgery, dilutions of Pseudomonas aeruginosa were introduced into the anterior chamber of both eyes. The eyes receiving gentamicin-enriched corneas showed mild to moderate infection; the contralateral eyes showed significantly more severe infection. The results indicated that donor corneas stored in gentamicin-enriched M-K medium inhibit the growth of bacteria acquired at the time of surgery and thus may improve the safety of such transplantation procedures. © 1986, American Medical Association. All rights reserved.
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| Data di pubblicazione: | 1986 | |
| Titolo: | Antibacterial Effect of Donor Corneas Stored in Gentamicin-Enriched McCarey-Kaufman Medium | |
| Autori: | Yau, Chi-Wang; Busin, Massimo; Avni, Isaac; Kaufman, Herbert E. | |
| Rivista: | ARCHIVES OF OPHTHALMOLOGY | |
| Keywords: | Ophthalmology | |
| Abstract in inglese: | Penetrating keratoplasty was performed on five pairs of rabbit eyes; one eye of each animal received a donor cornea stored in McCarey-Kaufman (M-K) medium containing gentamicin, and the contralateral eye received a donor cornea stored in M-K medium without gentamicin. At the end of surgery, dilutions of Pseudomonas aeruginosa were introduced into the anterior chamber of both eyes. The eyes receiving gentamicin-enriched corneas showed mild to moderate infection; the contralateral eyes showed significantly more severe infection. The results indicated that donor corneas stored in gentamicin-enriched M-K medium inhibit the growth of bacteria acquired at the time of surgery and thus may improve the safety of such transplantation procedures. © 1986, American Medical Association. All rights reserved. | |
| Digital Object Identifier (DOI): | 10.1001/archopht.1986.01050140121032 | |
| Handle: | http://hdl.handle.net/11392/2418184 | |
| Appare nelle tipologie: | 03.1 Articolo su rivista |
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