Safety and short-term efficacy of telangiectasia treatment by means of an innovative combination of 532 and 808 nm transdermal diode laser

Objectives To evaluate the safety and efficacy of an innovative transdermal multiple wavelength diode laser in telangiectasia treatment. Methods A total of 94 females underwent treatment by means of a multiple wavelength laser. All the cases were treated by three cycles of 532 nm combined with simultaneous 808 nm pulse. OFF time between the cycles was 10 ms. The handling physician, the patient and a blind assessor scored the aesthetic outcome in a range from 0 (no change) to 10 (100% disappearance). Pain was scored from 0 (no pain) to 10 (most painful experience ever) by the patient. Results At 5 +/- 1 months, depigmentation was observed in 3/94 cases (3.2%), hyperpigmentation in (4/94 4.2%), transient erythema in 14/94 (14.9%), transient oedema in 11/94 (11.7%), matting in 1/94 (1.1%). Mean aesthetic outcome was scored as 7.9 +/- 1.3 by the physician, 7.7 +/- 1 by the independent assessor and 7.2 +/- 2.4 by the patient. Patients reported a mean peri-procedural pain of 3.4 +/- 1.5. Conclusions The simultaneous application of 532 nm and 808 nm laser emission is safe and effective in 0.1-1 mm telangiectasia treatment. The present investigation provides data for a deeper insight into the biology of the tissue photo-modulation.