Non-atrophic lesions of the small bowel mucosa are characterised by minimal intestinal lesions with an increased number of intraepithelial lymphocytes (IEL), with or without crypt hyperplasia and in presence of a normal architecture of intestinal villi. Minimal intestinal lesions, though non-specific for coeliac disease (CD), are included in the wide spectrum of gluten-dependent histological damage and they can be an expression of potential CD. However, they can be a sign of many disorders other than gluten-sensitive enteropathy. Therefore, it is important to differentiate patients with gluten-dependent intestinal damage from those with non gluten- dependent intestinal lesions in order to plan the correct treatment and follow-up.

Gluten- and non-gluten-dependent non-atrophic lesions: the clinician and the pathologist viewpoint

Caio G
Co-primo
;
2010

Abstract

Non-atrophic lesions of the small bowel mucosa are characterised by minimal intestinal lesions with an increased number of intraepithelial lymphocytes (IEL), with or without crypt hyperplasia and in presence of a normal architecture of intestinal villi. Minimal intestinal lesions, though non-specific for coeliac disease (CD), are included in the wide spectrum of gluten-dependent histological damage and they can be an expression of potential CD. However, they can be a sign of many disorders other than gluten-sensitive enteropathy. Therefore, it is important to differentiate patients with gluten-dependent intestinal damage from those with non gluten- dependent intestinal lesions in order to plan the correct treatment and follow-up.
2010
Volta, U; Caio, G; Tavani, E; Adorno, A.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2407806
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