The Senegalese sole has become one of the most promising species for the Spanish aquaculture, with annual increments in production of around 20% in the last years. These positive figures are the consequence of years of scientific research and technological development. Nevertheless, unsolved problems still persist, such as susceptibility to pathologies, unbalanced sex ratios and reduced efficiency of wild broodstock, which is almost complete in the case of cultured broodstock.. In previous projects, we analyzed the role of the pineal organ and melatonin in transducing environmental information, the neuroendocrine control of reproduction and the gonadotropin-inhibitory hormone (Reprosole and Cronosolea), the endocrine interactions along the reproductive axis (Soler and Reprosole), the ontogeny of the circadian clock under different light and temperature conditions and its influence on sex determination/differentiation (Circasole and Cronosolea). In our previous project (SOLEMBRYO) we started the study of the mechanisms for light and temperature sensing, the epigenetic effects provoked by the environment, and deepened into the study of the neuroendocrine system of sole in the early stages of development. We also found cones sensitive to blue (lmax 470 nm), green (lmax 530 nm) and red (lmax 550 nm) lights, as well as rods (lmax 511 nm) in the retina of sole, and most interestingly, marked differences in opsin and thermosensing channels expression along the life cycle of sole. Our working hypothesis in BLUESOLE poses that light and temperature requirements for sole might change during life time and thus, be different for embryos, larvae, fingerlings, juveniles and broodstock. Thus, the general objective of the proposal is to deepen into the investigation of the mechanisms of photo-/thermo-reception to optimize key environmental factors for sole aquaculture, adjusting light and temperature according to the needs of fish at different life stages, with the aim of boosting sole growth, normal development, welfare and reproduction. BLUESOLE gathers 3 complementary teams with expertises in neuroanatomy, neuroendocrinology and molecular biology (UCA), chronobiology and animal physiology (UMU), and endocrine control of reproduction (CSIC). The proposal contains original scientific and technological elements, including transcriptomic, proteomic, epigenomic and genome editing (CRISPR-Cas) approaches. The expected impact of the results is high at scientific level (new knowledge creation) and technological level (development of new biothecnological tools), which will be transferred to the industry through the design & development of novel blue LED lights and environmental control protocols. These activities could be framed within challenge no 2: Seguridad y Calidad Alimentaria; Actividad Agraria Productiva y Sostenible; Sostenibilidad de Recursos Naturales, Investigación Marina y Marítima" of the Spanish Scientific, Technological and Innovation strategy (2013-2020), and pursuit EU priority topics of H2020 such as blue growth, aimed at promoting ecosystem-based aquaculture.

“BLUESOLE: Blue growth and sole aquaculture - Use of new blue LED illumination and cycles of light and temperature to improve the rhythms of reproduction, development and growth” (AGL2017-82582-C3-3-R).

Bertolucci cristiano
2018

Abstract

The Senegalese sole has become one of the most promising species for the Spanish aquaculture, with annual increments in production of around 20% in the last years. These positive figures are the consequence of years of scientific research and technological development. Nevertheless, unsolved problems still persist, such as susceptibility to pathologies, unbalanced sex ratios and reduced efficiency of wild broodstock, which is almost complete in the case of cultured broodstock.. In previous projects, we analyzed the role of the pineal organ and melatonin in transducing environmental information, the neuroendocrine control of reproduction and the gonadotropin-inhibitory hormone (Reprosole and Cronosolea), the endocrine interactions along the reproductive axis (Soler and Reprosole), the ontogeny of the circadian clock under different light and temperature conditions and its influence on sex determination/differentiation (Circasole and Cronosolea). In our previous project (SOLEMBRYO) we started the study of the mechanisms for light and temperature sensing, the epigenetic effects provoked by the environment, and deepened into the study of the neuroendocrine system of sole in the early stages of development. We also found cones sensitive to blue (lmax 470 nm), green (lmax 530 nm) and red (lmax 550 nm) lights, as well as rods (lmax 511 nm) in the retina of sole, and most interestingly, marked differences in opsin and thermosensing channels expression along the life cycle of sole. Our working hypothesis in BLUESOLE poses that light and temperature requirements for sole might change during life time and thus, be different for embryos, larvae, fingerlings, juveniles and broodstock. Thus, the general objective of the proposal is to deepen into the investigation of the mechanisms of photo-/thermo-reception to optimize key environmental factors for sole aquaculture, adjusting light and temperature according to the needs of fish at different life stages, with the aim of boosting sole growth, normal development, welfare and reproduction. BLUESOLE gathers 3 complementary teams with expertises in neuroanatomy, neuroendocrinology and molecular biology (UCA), chronobiology and animal physiology (UMU), and endocrine control of reproduction (CSIC). The proposal contains original scientific and technological elements, including transcriptomic, proteomic, epigenomic and genome editing (CRISPR-Cas) approaches. The expected impact of the results is high at scientific level (new knowledge creation) and technological level (development of new biothecnological tools), which will be transferred to the industry through the design & development of novel blue LED lights and environmental control protocols. These activities could be framed within challenge no 2: Seguridad y Calidad Alimentaria; Actividad Agraria Productiva y Sostenible; Sostenibilidad de Recursos Naturales, Investigación Marina y Marítima" of the Spanish Scientific, Technological and Innovation strategy (2013-2020), and pursuit EU priority topics of H2020 such as blue growth, aimed at promoting ecosystem-based aquaculture.
In corso di stampa
Internazionale
Responsabile di Unità locale
Nessun Finanziamento
Bertolucci, Cristiano
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2398576
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