Pharmacological activation of the P2X4 receptor expressed by brain microglia may provide a novel avenue to promote remyelination and improve clinical symptoms in experimental autoimmune encephalomyelitis and potentially in multiple sclerosis.
Microglia P2X4 receptors as pharmacological targets for demyelinating diseases
Di Virgilio, Francesco
Primo
;Sarti, Alba ClaraUltimo
2018
Abstract
Pharmacological activation of the P2X4 receptor expressed by brain microglia may provide a novel avenue to promote remyelination and improve clinical symptoms in experimental autoimmune encephalomyelitis and potentially in multiple sclerosis.File in questo prodotto:
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EMBO Mol Med - 2018 - Di Virgilio - Microglia P2X4 receptors as pharmacological targets for demyelinating diseases.pdf
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