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EnglishIn previous decades, pediatric liver transplantation has become a state-of-the-art operation with excellent success and limited mortality. Graft and patient survival have continued to improve as a result of improvements in medical, surgical and anesthetic management, organ availability, immunosuppression, and identification and treatment of postoperative complications. The utilization of split-liver grafts and living-related donors has provided more organs for pediatric patients. Newer immunosuppression regimens, including induction therapy, have had a significant impact on graft and patient survival. Future developments of pediatric liver transplantation will deal with long-term follow-up, with prevention of immunosuppression-related complications and promotion of as normal growth as possible. This review describes the state-of-the-art in pediatric liver transplantation
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| Data di pubblicazione: | 2009 | |
| Titolo: | Pediatric liver transplantation. | |
| Autori: | Spada, M; Riva, S; Maggiore, G; Cintorino, D; Gridelli, B. | |
| Rivista: | WORLD JOURNAL OF GASTROENTEROLOGY | |
| Keywords: | Liver transplantation; child | |
| Abstract in inglese: | In previous decades, pediatric liver transplantation has become a state-of-the-art operation with excellent success and limited mortality. Graft and patient survival have continued to improve as a result of improvements in medical, surgical and anesthetic management, organ availability, immunosuppression, and identification and treatment of postoperative complications. The utilization of split-liver grafts and living-related donors has provided more organs for pediatric patients. Newer immunosuppression regimens, including induction therapy, have had a significant impact on graft and patient survival. Future developments of pediatric liver transplantation will deal with long-term follow-up, with prevention of immunosuppression-related complications and promotion of as normal growth as possible. This review describes the state-of-the-art in pediatric liver transplantation | |
| Handle: | http://hdl.handle.net/11392/2387202 | |
| Appare nelle tipologie: | 03.1 Articolo su rivista |
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