Invasive solid papillary breast carcinoma resembling the tall cell variant of papillary thyroid neoplasms (BPTC) is an infrequent entity, unrelated to thyroid carcinoma, with 40 cases described in literature. Histologically it is composed of bland looking neoplastic epithelial cells arranged in papillary, solid, and follicular structures, separated by fibrous bands. Cells have abundant eosinophilic cytoplasm and nuclei show occasional grooving and inclusions. Psammoma bodies or granular calcifications can be seen as well as eosinophilic/amphophilic colloid-like secretions. These tumors display a triple-negative profile although associated with low aggressive potential. We report a new case diagnosed at our institution earlier in 2017.
A case of invasive solid papillary breast carcinoma resembling tall cell variant of papillary thyroid carcinoma
Pedriali, M;BONAZZA, Simona;Querzoli, P
2017
Abstract
Invasive solid papillary breast carcinoma resembling the tall cell variant of papillary thyroid neoplasms (BPTC) is an infrequent entity, unrelated to thyroid carcinoma, with 40 cases described in literature. Histologically it is composed of bland looking neoplastic epithelial cells arranged in papillary, solid, and follicular structures, separated by fibrous bands. Cells have abundant eosinophilic cytoplasm and nuclei show occasional grooving and inclusions. Psammoma bodies or granular calcifications can be seen as well as eosinophilic/amphophilic colloid-like secretions. These tumors display a triple-negative profile although associated with low aggressive potential. We report a new case diagnosed at our institution earlier in 2017.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
