A comprehensive study on essential oil samples of Foeniculum vulgare Miller from Tarquinia (Italy) is reported. A 24-h systematic steam distillation was performed on different harvested samples applying different extraction times. The GC-MS analysis of the residue outcome showed o-cymene, Î±-phellandrene, Î±-pinene and estragole as the major constituents. The predominance and continued presence of o-cymene makes this fennel oil a rather unique chemotype. An evident correlation between the antifungal activity and phenological stage is demonstrated. The most active fractions were particularly rich in estragole, as well as a significant amount of fenchone that possibly exerts some additive effect in the expression of overall antifungal potency. Pre-fruiting material produced oil particularly rich in o-cymene. With reference to the duration of the extraction, the maximum amount of oil was released within the first 3Â h, whereas the reproductive phase material needed at least 6Â h for the extraction.
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|Titolo:||Essential oil extraction, chemical analysis and anti-Candida activity of Foeniculum vulgare Miller â new approaches|
|Data di pubblicazione:||2017|
|Appare nelle tipologie:||03.1 Articolo su rivista|