Background: Increasing age of first pregnancy among Italian women with premenopausal breast cancer makes adjuvant hormonal therapy a hot topic, justifying a survey on the therapeutic approach of Italian oncologists. Materials & methods: From April to July 2012, an 11-item electronic questionnaire was submitted to Italian oncologists and 611 out of 974 invited filled questionnaires were collected from all over Italy. Results: In total, 97.7% of patients aged <40 years needing only hormonal therapy would receive both tamoxifen and luteinizing hormone-releasing hormone agonists (LHRHa); 2.3% tamoxifen or LHRHa alone. For the majority of oncologists LHRHa was also the preferred choice to preserving fertility. Conclusion: Results are rather consistent with major guidelines but with a greater use of LHRHa and aromatase inhibitor.

Adjuvant hormonal therapy and fertility preservation in premenopausal breast cancer: A survey among Italian oncologists

FRASSOLDATI, Antonio;
2015

Abstract

Background: Increasing age of first pregnancy among Italian women with premenopausal breast cancer makes adjuvant hormonal therapy a hot topic, justifying a survey on the therapeutic approach of Italian oncologists. Materials & methods: From April to July 2012, an 11-item electronic questionnaire was submitted to Italian oncologists and 611 out of 974 invited filled questionnaires were collected from all over Italy. Results: In total, 97.7% of patients aged <40 years needing only hormonal therapy would receive both tamoxifen and luteinizing hormone-releasing hormone agonists (LHRHa); 2.3% tamoxifen or LHRHa alone. For the majority of oncologists LHRHa was also the preferred choice to preserving fertility. Conclusion: Results are rather consistent with major guidelines but with a greater use of LHRHa and aromatase inhibitor.
Barni, Sandro; Collovà, Elena; Frassoldati, Antonio; Amoroso, Domenico
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11392/2377794
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