This document presents the guidelines for the cerebrospinal fluid (CSF) analysis and the determination of oligoclonal bands (OCBs) as pivotal tests in neuroinflammatory pathologies of the central nervous system. The guidelines have been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on the pathologies in which the CSF analysis is indicated, and, particularly, on those characterized by the presence of OCBs in the intrathecal compartment, indications and limits of CSF analysis and OCB determination, instructions for result interpretation, and agreed laboratory protocols (Appendix) are reported for the communicative community of neurologists and clinical pathologists.

Cerebrospinal fluid analysis and the determination of oligoclonal bands

CASTELLAZZI, Massimiliano;FAINARDI, Enrico;
2017

Abstract

This document presents the guidelines for the cerebrospinal fluid (CSF) analysis and the determination of oligoclonal bands (OCBs) as pivotal tests in neuroinflammatory pathologies of the central nervous system. The guidelines have been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on the pathologies in which the CSF analysis is indicated, and, particularly, on those characterized by the presence of OCBs in the intrathecal compartment, indications and limits of CSF analysis and OCB determination, instructions for result interpretation, and agreed laboratory protocols (Appendix) are reported for the communicative community of neurologists and clinical pathologists.
Gastaldi, M; Zardini, E; Leante, R; Ruggieri, M; Costa, G; Cocco, E; De Luca, G; Cataldo, I; Biagioli, T; Ballerini, C; Castellazzi, Massimiliano; Fainardi, Enrico; Pettini, P; Zaffaroni, M; Giunti, D; Capello, E; Bernardi, G; Ciusani, E; Giannotta, C; Nobile orazio, E; Bazzigaluppi, E; Passerini, G; Bedin, R; Sola, P; Brivio, R; Cavaletti, G; Sala, A; Bertolotto, A; Desina, G; Leone, Ma; Mariotto, S; Ferrari, S; Paternoster, A; Giavarina, D; Lolli, F; Franciotta, D.
File in questo prodotto:
File Dimensione Formato  
Gastaldi CSF analysis 2017.pdf

solo gestori archivio

Descrizione: editoriale
Tipologia: Full text (versione editoriale)
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 392.26 kB
Formato Adobe PDF
392.26 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
aaa cerebrospinal fluid oligoclonal bands final.pdf

accesso aperto

Descrizione: Pre print
Tipologia: Pre-print
Licenza: PUBBLICO - Pubblico con Copyright
Dimensione 672.29 kB
Formato Adobe PDF
672.29 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2377105
Citazioni
  • ???jsp.display-item.citation.pmc??? 8
  • Scopus 22
  • ???jsp.display-item.citation.isi??? 23
social impact