Objective To investigate the diagnostic performance of ultrasound in predicting birth-weight (BW) discordance in twin pregnancy.Methods Electronic databases PubMed, EMBASE and CINAHL were searched using combinations of MeSH terms 'birth weight', 'discordance', 'twins' and ` ultrasound'. Summary estimates of sensitivity, specificity, positive and negative likelihood ratios and diagnostic odds ratios for the predictive accuracy of sonographically estimated fetal-weight (EFW) discordance and abdominal-circumference (AC) discordance in predicting BW discordance were computed using hierarchical summary receiver-operating characteristics curves.Results Twenty studies (including 5826 twin pregnancies) were included. EFW discordance >= 20% had a sensitivity of 65.4% and specificity of 90.8% in predicting BW discordance >= 20%. The predictive performance of ultrasound performed within 1 month, 2 weeks and 3 days before birth was 61.4%, 72.3% and 78.9%, respectively. EFW discordance >= 25% had a sensitivity of 57.7% and specificity of 95.2% in predicting BW discordance >= 25%. The sensitivity of EFW discordance >= 25% detected within 1 month, 2 weeks and 3 days before birth was 60.0%, 75.0% and 60.3%, respectively, while the corresponding values for specificity were 97.7%, 96.2% and 87.3%, respectively. In view of the different cut-offs reported among studies, it was not possible to perform comprehensive data synthesis for each AC discordance cut-off. The optimal diagnostic performance of AC discordance was for prediction of BW discordance >= 25%, with a sensitivity of 70.8% and specificity of 86.4%.Conclusion Ultrasound EFW discordance has an overall moderate accuracy in predicting BW discordance in twin pregnancy. Copyright (C) 2016 ISUOG. Published by John Wiley & Sons Ltd.

Diagnostic accuracy of ultrasound in predicting birth-weight discordance in twin pregnancy: systematic review and meta-analysis

MANZOLI, Lamberto;
2017

Abstract

Objective To investigate the diagnostic performance of ultrasound in predicting birth-weight (BW) discordance in twin pregnancy.Methods Electronic databases PubMed, EMBASE and CINAHL were searched using combinations of MeSH terms 'birth weight', 'discordance', 'twins' and ` ultrasound'. Summary estimates of sensitivity, specificity, positive and negative likelihood ratios and diagnostic odds ratios for the predictive accuracy of sonographically estimated fetal-weight (EFW) discordance and abdominal-circumference (AC) discordance in predicting BW discordance were computed using hierarchical summary receiver-operating characteristics curves.Results Twenty studies (including 5826 twin pregnancies) were included. EFW discordance >= 20% had a sensitivity of 65.4% and specificity of 90.8% in predicting BW discordance >= 20%. The predictive performance of ultrasound performed within 1 month, 2 weeks and 3 days before birth was 61.4%, 72.3% and 78.9%, respectively. EFW discordance >= 25% had a sensitivity of 57.7% and specificity of 95.2% in predicting BW discordance >= 25%. The sensitivity of EFW discordance >= 25% detected within 1 month, 2 weeks and 3 days before birth was 60.0%, 75.0% and 60.3%, respectively, while the corresponding values for specificity were 97.7%, 96.2% and 87.3%, respectively. In view of the different cut-offs reported among studies, it was not possible to perform comprehensive data synthesis for each AC discordance cut-off. The optimal diagnostic performance of AC discordance was for prediction of BW discordance >= 25%, with a sensitivity of 70.8% and specificity of 86.4%.Conclusion Ultrasound EFW discordance has an overall moderate accuracy in predicting BW discordance in twin pregnancy. Copyright (C) 2016 ISUOG. Published by John Wiley & Sons Ltd.
Leombroni, M.; Liberati, M.; Fanfani, F.; Pagani, G.; Familiari, A.; Buca, D.; Manzoli, Lamberto; Scambia, G.; Rizzo, G.; D'Antonio, F.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2376660
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