Technological innovation and knowledge have always conditioned surgery. What will be the role of surgery in the future is under discussion. Genotyping might leads the path towards personalized medical therapies. In this mini review we have compared the assumptions contained in them in order to assess whether the new diagnostic and therapeutic possibility will be able to affect surgical options in the near future. Methods: We analyzed articles extracted from Medscape and Pubmed using some key words related to Colon cancer. Genotyping, molecular and personalized medicine and we have compared the assumptions contained in them. Discussion and Conclusion: Research about has not yet demonstrates its potentiality but, in the future it is conceivable that molecular medicine may lead the full personalized treatment plan where the need for surgery will depend upon the relationship between the individual genotype and a constellation of factors, able to influence the effectiveness of surgery. Then, we introduce the concept of “surgeromic”, a neologism binding surgery to its individual determinants and assume some research areas to be implemented in order to overcome some obstacles to the full development of this new era.

There will be a “Surgeromic “ in our future? Where the research on colorectal cancer is leading Surgery

RUBBINI, Michele
2017

Abstract

Technological innovation and knowledge have always conditioned surgery. What will be the role of surgery in the future is under discussion. Genotyping might leads the path towards personalized medical therapies. In this mini review we have compared the assumptions contained in them in order to assess whether the new diagnostic and therapeutic possibility will be able to affect surgical options in the near future. Methods: We analyzed articles extracted from Medscape and Pubmed using some key words related to Colon cancer. Genotyping, molecular and personalized medicine and we have compared the assumptions contained in them. Discussion and Conclusion: Research about has not yet demonstrates its potentiality but, in the future it is conceivable that molecular medicine may lead the full personalized treatment plan where the need for surgery will depend upon the relationship between the individual genotype and a constellation of factors, able to influence the effectiveness of surgery. Then, we introduce the concept of “surgeromic”, a neologism binding surgery to its individual determinants and assume some research areas to be implemented in order to overcome some obstacles to the full development of this new era.
Rubbini, Michele
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11392/2374499
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