Objectives/Hypothesis: To evaluate if upper airway surgery reduces blood pressure in patients with obstructive sleep apnea (OSA). Study Design: Prospective series. Methods: A prospective series of 112 consecutive OSA patients with hypertension (HTN). All patients were > 18 years old, respiratory disturbance index >5, all levels of apnea-hypopnea index (AHI), with a history of HTN treated with medication for at least 6 months. Surgical procedures included septoplasty, turbinate reduction, palate surgery, and tongue base reduction. Results: There were 92 men and 20 women, with a mean age of 48.6 years, mean body mass index (BMI) was 27.5 (range, 19.7–34.7). Mean follow-up was 16.1 months. The mean preoperative AHI was 32.6 (range, 1.2–104), with the mean lowest oxygen saturation (LSAT) of 79.9% (range, 52%–93%). The mean adjusted preoperative and postoperative systolic blood pressure (SBP) was reduced from 146 ± 15.3 mm Hg to 122 ± 12.5 mm Hg (P <.001), and diastolic blood pressure (DBP) was reduced from 91 ± 10.2 mm Hg to 76 ± 7.8 mm Hg (P <.001). There was a decrease in overall BMI from 27.5 ± 3.6 to 25.5 ± 3.0 (P <.001); however, based on multivariate analysis, the reduction in SBP and DBP was not affected by this BMI reduction. Fifty-eight patients (51.8%) did not require their antihypertensive after surgery. There was poor correlation noted between HTN with AHI, LSAT, and oxygen duration <90%. Conclusions: Upper airway surgery does reduce SBP and DBP in patients with OSA. Level of Evidence: 4. Laryngoscope, 128:523–527, 2018.

Upper airway surgery for obstructive sleep apnea reduces blood pressure

VICINI, Claudio;
2018

Abstract

Objectives/Hypothesis: To evaluate if upper airway surgery reduces blood pressure in patients with obstructive sleep apnea (OSA). Study Design: Prospective series. Methods: A prospective series of 112 consecutive OSA patients with hypertension (HTN). All patients were > 18 years old, respiratory disturbance index >5, all levels of apnea-hypopnea index (AHI), with a history of HTN treated with medication for at least 6 months. Surgical procedures included septoplasty, turbinate reduction, palate surgery, and tongue base reduction. Results: There were 92 men and 20 women, with a mean age of 48.6 years, mean body mass index (BMI) was 27.5 (range, 19.7–34.7). Mean follow-up was 16.1 months. The mean preoperative AHI was 32.6 (range, 1.2–104), with the mean lowest oxygen saturation (LSAT) of 79.9% (range, 52%–93%). The mean adjusted preoperative and postoperative systolic blood pressure (SBP) was reduced from 146 ± 15.3 mm Hg to 122 ± 12.5 mm Hg (P <.001), and diastolic blood pressure (DBP) was reduced from 91 ± 10.2 mm Hg to 76 ± 7.8 mm Hg (P <.001). There was a decrease in overall BMI from 27.5 ± 3.6 to 25.5 ± 3.0 (P <.001); however, based on multivariate analysis, the reduction in SBP and DBP was not affected by this BMI reduction. Fifty-eight patients (51.8%) did not require their antihypertensive after surgery. There was poor correlation noted between HTN with AHI, LSAT, and oxygen duration <90%. Conclusions: Upper airway surgery does reduce SBP and DBP in patients with OSA. Level of Evidence: 4. Laryngoscope, 128:523–527, 2018.
Pang, Kenny P; Pang, Edward B; Pang, Kathleen A; Vicini, Claudio; Chan, Yiong Huak; Rotenberg, Brian W.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11392/2374495
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