Changes in endometrial leukocyte subpopulations and most of all in the percentage of uterine natural-killer cells (uNK), during the menstrual cycles, may have a pivotal role in the implantation process. An increase of activated NK cells (CD56dim CD16+ CD69+) in the peripheral blood of patients with a reduced rate of embryo implantation in IVF treatment has been reported elsewhere, but we found, by using flow cytometry, normal endometrial lymphocyte subpopulations in young patients with a history of repeated unexplained implantation failure who were undergoing IVF cycles for idiopathic infertility. © 2007 American Society for Reproductive Medicine.
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Data di pubblicazione: | 2007 | |
Titolo: | Normal percentage of CD56bright natural killer cells in young patients with a history of repeated unexplained implantation failure after in vitro fertilization cycles | |
Autori: | Matteo, Maria G; Greco, Pantaleo; Rosenberg, Piergiorgio; Mestice, Anna; Baldini, Domenico; Falagario, Teresa; Martino, Vincenzo; Santodirocco, Michele; Massenzio, Francesca; Castellana, Laura; Specchia, Giorgina; Liso, Arcangelo | |
Rivista: | FERTILITY AND STERILITY | |
Parole Chiave: | Adult; Antigens, CD56; Embryo Transfer; Female; Flow Cytometry; Humans; Killer Cells, Natural; Uterus; Embryo Implantation; Fertilization in Vitro; Reproductive Medicine; Obstetrics and Gynecology | |
Abstract in inglese: | Changes in endometrial leukocyte subpopulations and most of all in the percentage of uterine natural-killer cells (uNK), during the menstrual cycles, may have a pivotal role in the implantation process. An increase of activated NK cells (CD56dim CD16+ CD69+) in the peripheral blood of patients with a reduced rate of embryo implantation in IVF treatment has been reported elsewhere, but we found, by using flow cytometry, normal endometrial lymphocyte subpopulations in young patients with a history of repeated unexplained implantation failure who were undergoing IVF cycles for idiopathic infertility. © 2007 American Society for Reproductive Medicine. | |
Digital Object Identifier (DOI): | 10.1016/j.fertnstert.2007.01.028 | |
Handle: | http://hdl.handle.net/11392/2372086 | |
Appare nelle tipologie: | 03.1 Articolo su rivista |