Sarcoidosis is a systemic granulomatous disorder of unknown etiology, which can involve the skin. Subcutaneous sarcoidosis is a rare variant of the cutaneous sarcoidosis, typically presenting as single or multiple indurated plaques on the upper extremities. It is closely associated with systemic manifestations, mainly lung involvement, although response to treatment and prognosis remain good. We report the case of a 58 year-old woman with subcutaneous manifestations associated with lung infiltrates and mediastinal and paratracheal adenopathy. Cutaneous and pulmonary involvement as well as mediastinal lymphadenopathy rapidly regressed without any systemic treatment. HLA typing was performed to evaluate the potential role of an immunogenetic predisposition factor.
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|Titolo:||A case of subcutaneous sarcoidosis: Considerations on genetic characterization, clinical presentation and course|
|Data di pubblicazione:||2017|
|Appare nelle tipologie:||03.1 Articolo su rivista|