One must always be aware that external influences may affect the interpretation of study results, the process of drug approval, and the economical analyses of pharmaceutical agents. Companies often have an important say in the definition of the research question, in the selection of patients, the way of reporting drop-outs, and adverse events. Furthermore, industry-financed cost-effectiveness analyses are more likely to support additional expenditures on investigational drugs than standard treatments.On the other hand, we have to recognize the pivotal role of the pharmaceutical industry in biomedical research since, given the lack of public funding, the majority of funded clinical trials in Europe and in the Americas is supported by industry. There are examples of government-funded clinical trials that changed the course of a disease, but they are scanty.
A way forward to the elimination of conflict of interest for experts involved in regulatory medicine and guidelines
CECONI, Claudio
2015
Abstract
One must always be aware that external influences may affect the interpretation of study results, the process of drug approval, and the economical analyses of pharmaceutical agents. Companies often have an important say in the definition of the research question, in the selection of patients, the way of reporting drop-outs, and adverse events. Furthermore, industry-financed cost-effectiveness analyses are more likely to support additional expenditures on investigational drugs than standard treatments.On the other hand, we have to recognize the pivotal role of the pharmaceutical industry in biomedical research since, given the lack of public funding, the majority of funded clinical trials in Europe and in the Americas is supported by industry. There are examples of government-funded clinical trials that changed the course of a disease, but they are scanty.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
