Le epatiti autoimmuni sieronegative in età pediatrica

Diagnosis of autoimmune hepatitis lies in few biochemical and histological features. None of them is essential and absence of conventional autoantibodies (ANA, SMA, LKM) determines the so called seronegative autoimmune hepatitis. This entity is accepted and well defined in adult patients while descriptions in childhood are rare. Herewe propose a first analysis of existingdata, matched with our personal experience, and we attempt to draw an initial description of this group of disorders.