Recent studies suggested that colorectal cancer influences the types and quantity of nucleic acids - especially microRNAs – detected in the bloodstream. Concentration of circulating (cell-free) microRNAs, and possibly of other non-coding RNAs, could therefore serve as valuable colorectal cancer biomarker and could deliver insight into the disease process. This chapter addresses the recent discoveries on circulating microRNA and long non-coding RNA as diagnostic or prognostic biomarkers in colorectal cancer.
Circulating non-coding RNA as biomarkers in colorectal cancer
LUPINI, Laura;MANGOLINI, Alessandra;NEGRINI, Massimo
2016
Abstract
Recent studies suggested that colorectal cancer influences the types and quantity of nucleic acids - especially microRNAs – detected in the bloodstream. Concentration of circulating (cell-free) microRNAs, and possibly of other non-coding RNAs, could therefore serve as valuable colorectal cancer biomarker and could deliver insight into the disease process. This chapter addresses the recent discoveries on circulating microRNA and long non-coding RNA as diagnostic or prognostic biomarkers in colorectal cancer.File in questo prodotto:
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