Recent studies suggested that colorectal cancer influences the types and quantity of nucleic acids - especially microRNAs – detected in the bloodstream. Concentration of circulating (cell-free) microRNAs, and possibly of other non-coding RNAs, could therefore serve as valuable colorectal cancer biomarker and could deliver insight into the disease process. This chapter addresses the recent discoveries on circulating microRNA and long non-coding RNA as diagnostic or prognostic biomarkers in colorectal cancer.

Circulating non-coding RNA as biomarkers in colorectal cancer

LUPINI, Laura;MANGOLINI, Alessandra;NEGRINI, Massimo
2016

Abstract

Recent studies suggested that colorectal cancer influences the types and quantity of nucleic acids - especially microRNAs – detected in the bloodstream. Concentration of circulating (cell-free) microRNAs, and possibly of other non-coding RNAs, could therefore serve as valuable colorectal cancer biomarker and could deliver insight into the disease process. This chapter addresses the recent discoveries on circulating microRNA and long non-coding RNA as diagnostic or prognostic biomarkers in colorectal cancer.
2016
978-3-319-42057-8
978-3-319-42059-2
Biomarkers; Colorectal cancer; Diagnostics; MicroRNA; Plasma; Serum; Medicine (all); Biochemistry, Genetics and Molecular Biology (all)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/2368234
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