Operator-independent quantitative chest computed tomography versus standard assessment of interstitial lung disease related to systemic sclerosis: A multi-centric study

Interstitial lung disease (ILD) related to systemic sclerosis (SSc) is assessed with pulmonary functional tests (PFTs) and semi-quantitative scores based on extent of ILD detectable on chest computed tomography (CT). CT quantitative indexes (QCTIs) are promising tools to assess extent of ILD. This study's aim is to evaluate the validity of QCTI compared with that of chest CT standard evaluation and PFTs. Moreover, QCTI differences between patients' subgroups according to prognostic stratifications were investigated.

Data di pubblicazione: 2015
Titolo: Operator-independent quantitative chest computed tomography versus standard assessment of interstitial lung disease related to systemic sclerosis: A multi-centric study
Autori: Ariani, Alarico; Silva, Mario; Bravi, Elena; Saracco, Marta; Parisi, Simone; De Gennaro, Fabio; Lumetti, Federica; Idolazzi, Luca; Seletti, Valeria; Caramaschi, Paola; Benini, Camilla; Bodini, Flavio Cesare; Scirè, Carlo Alberto; Lucchini, Gianluca; Santilli, Daniele; Mozzani, Flavio; Imberti, Davide; Arrigoni, Eugenio; Delsante, Giovanni; Pellerito, Raffaele; Fusaro, Enrico; Sverzellati, Nicola
Rivista: MODERN RHEUMATOLOGY
Parole Chiave: CT indexes; CT quantitative assessment; Interstitial lung disease; OsiriX; Systemic sclerosis; Diagnosis, Differential; Female; Humans; Lung Diseases, Interstitial; Male; Middle Aged; Prognosis; ROC Curve; Respiratory Function Tests; Scleroderma, Systemic; Tomography, X-Ray Computed
Abstract: Interstitial lung disease (ILD) related to systemic sclerosis (SSc) is assessed with pulmonary functional tests (PFTs) and semi-quantitative scores based on extent of ILD detectable on chest computed tomography (CT). CT quantitative indexes (QCTIs) are promising tools to assess extent of ILD. This study's aim is to evaluate the validity of QCTI compared with that of chest CT standard evaluation and PFTs. Moreover, QCTI differences between patients' subgroups according to prognostic stratifications were investigated.
Digital Object Identifier (DOI): 10.3109/14397595.2015.1016200
Handle: http://hdl.handle.net/11392/2365701
Appare nelle tipologie:03.1 Articolo su rivista

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