Interstitial lung disease (ILD) related to systemic sclerosis (SSc) is assessed with pulmonary functional tests (PFTs) and semi-quantitative scores based on extent of ILD detectable on chest computed tomography (CT). CT quantitative indexes (QCTIs) are promising tools to assess extent of ILD. This study's aim is to evaluate the validity of QCTI compared with that of chest CT standard evaluation and PFTs. Moreover, QCTI differences between patients' subgroups according to prognostic stratifications were investigated.
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Data di pubblicazione: | 2015 | |
Titolo: | Operator-independent quantitative chest computed tomography versus standard assessment of interstitial lung disease related to systemic sclerosis: A multi-centric study | |
Autori: | Ariani, Alarico; Silva, Mario; Bravi, Elena; Saracco, Marta; Parisi, Simone; De Gennaro, Fabio; Lumetti, Federica; Idolazzi, Luca; Seletti, Valeria; Caramaschi, Paola; Benini, Camilla; Bodini, Flavio Cesare; Scirè, Carlo Alberto; Lucchini, Gianluca; Santilli, Daniele; Mozzani, Flavio; Imberti, Davide; Arrigoni, Eugenio; Delsante, Giovanni; Pellerito, Raffaele; Fusaro, Enrico; Sverzellati, Nicola | |
Rivista: | MODERN RHEUMATOLOGY | |
Parole Chiave: | CT indexes; CT quantitative assessment; Interstitial lung disease; OsiriX; Systemic sclerosis; Diagnosis, Differential; Female; Humans; Lung Diseases, Interstitial; Male; Middle Aged; Prognosis; ROC Curve; Respiratory Function Tests; Scleroderma, Systemic; Tomography, X-Ray Computed | |
Abstract: | Interstitial lung disease (ILD) related to systemic sclerosis (SSc) is assessed with pulmonary functional tests (PFTs) and semi-quantitative scores based on extent of ILD detectable on chest computed tomography (CT). CT quantitative indexes (QCTIs) are promising tools to assess extent of ILD. This study's aim is to evaluate the validity of QCTI compared with that of chest CT standard evaluation and PFTs. Moreover, QCTI differences between patients' subgroups according to prognostic stratifications were investigated. | |
Digital Object Identifier (DOI): | 10.3109/14397595.2015.1016200 | |
Handle: | http://hdl.handle.net/11392/2365701 | |
Appare nelle tipologie: | 03.1 Articolo su rivista |
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