Period: 48 months (from 01/12/2011 to 30/11/2015) Project n°: 098/GR-2009-1596647 Funded by: Ministero della Salute-Bando Giovani Ricercatori 2009-Development of a high efficient method, based on the technology of surface plasmon resonance(SPR)-Imaging combined with the use peptide-nucleic acids (PNA) probes, enabling the identification of point mutations without amplification by polymerase-chain reaction (PCR). The accuracy and the detection efficiency make this approach suitable for non-invasive prenatal diagnosis based on the analysis of the fetal-free cell DNA within the peripheral blood of pregnant women.
Titolo del progetto: Sviluppo di strategie non invasive per la diagnosi prenatale di malattie rare attraverso Imaging basata su risonanza plasmonica di superficie (SPR-Imaging), acidi peptido-nucleici e ibridazione senza PCR. Durata: 48 mesi (dal 01/12/2011 al 30/11/2015) Progetto n°: 098/GR-2009-1596647 Finanziato da: Ministero della Salute-Bando Giovani Ricercatori 2009
BORGATTI, Monica
Primo
Funding Acquisition
;GUERRA, GiovanniPenultimo
;
2011
Abstract
Period: 48 months (from 01/12/2011 to 30/11/2015) Project n°: 098/GR-2009-1596647 Funded by: Ministero della Salute-Bando Giovani Ricercatori 2009-Development of a high efficient method, based on the technology of surface plasmon resonance(SPR)-Imaging combined with the use peptide-nucleic acids (PNA) probes, enabling the identification of point mutations without amplification by polymerase-chain reaction (PCR). The accuracy and the detection efficiency make this approach suitable for non-invasive prenatal diagnosis based on the analysis of the fetal-free cell DNA within the peripheral blood of pregnant women.File in questo prodotto:
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