A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a triparite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.
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Data di pubblicazione: | 2001 | |
Titolo: | The tripartite motif family identifies cell compartments | |
Autori: | Reymond, A. Meroni, G. Fantozzi, A. Merla, G. Cairo, S. Luzi, L. Riganelli, D. Zanaria, E. Messali, S. Cainarca, S. Guffanti, A. Minucci, S. Pelicci, P.G. Ballabio, A. | |
Rivista: | EMBO JOURNAL | |
Abstract in inglese: | A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a triparite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments. | |
Digital Object Identifier (DOI): | 10.1093/emboj/20.9.2140 | |
Handle: | http://hdl.handle.net/11392/2353062 | |
Appare nelle tipologie: | 03.1 Articolo su rivista |
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