In many scientific disciplines when dealing with complex problems, as for instance with comparisons between two or more groups, the NonParametric Combination (NPC) methodology offers an innovative but well tested approach thet frees the researcher from stringent assumptions of parametric methods and allowas a more flexible analysis both in terms of specification of multivariate hypotheses and in terms of the nature of the variables involved in the analysis. Moreover, one of the most relevant features of NPC tests is that they do not need modeling the dependence among variables and partial tests. IN this paper we introduce and illustrate the NPC methodology applying the statostiocal software "NPC Test" in a biomedical study.
Statistical Analysis in biomedical studies: an application of NPC Test to a clinical trial on a respiratory drug
BONNINI, Stefano;
2003
Abstract
In many scientific disciplines when dealing with complex problems, as for instance with comparisons between two or more groups, the NonParametric Combination (NPC) methodology offers an innovative but well tested approach thet frees the researcher from stringent assumptions of parametric methods and allowas a more flexible analysis both in terms of specification of multivariate hypotheses and in terms of the nature of the variables involved in the analysis. Moreover, one of the most relevant features of NPC tests is that they do not need modeling the dependence among variables and partial tests. IN this paper we introduce and illustrate the NPC methodology applying the statostiocal software "NPC Test" in a biomedical study.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
