Sonohysterosalpingography: A suitable choice in infertility workup

Purpose: To evaluate efficacy, compliance, and cost effectiveness of sonohysterosalpingography (HyCoSy) when compared to hysteroscopy for uterine cavity evaluation and to RX-hysterosalpingography (RX-HSG) for tubal patency determination. Methods: Three hundred and eight infertile patients underwent HyCoSy, hysteroscopy, and RX-HSG. We compared sensitivity, specificity, positive and negative predictive values (PPV and NPV), discomfort level, and cost of all three procedures. Results: HyCoSy presents elevated values of sensitivity, specificity, PPV, and NPV with no significant differences when compared to hysteroscopy. HyCoSy also has the same accuracy as RX-HSG. Pain perception and cost were higher with RX-HSG and hysteroscopy than with HyCoSy. Conclusions: HyCoSy can be considered as a first-line procedure for evaluation of the uterine cavity and tubal patency in infertile patients.