Human leucocyte antigen-G (HLA-G) is a non-classical HLA class I molecule with an important role at the fetus-maternal interface, preventing fetus recognition and abortion. The role of HLA-G as an immune-modulatory and anti-inflammatory molecule has led to investigate its role in pathological conditions. In these years, HLA-G has been shown to have an important implication in inflammatory pathologies. The focus of this review is to up-date the scientific knowledge on the expression of HLA-G molecules in inflammatory conditions.

New insights into HLA-G and inflammatory diseases

RIZZO, Roberta
Primo
;
BORTOLOTTI, Daria
Secondo
;
BARICORDI, Olavio;FAINARDI, Enrico
Ultimo
2012

Abstract

Human leucocyte antigen-G (HLA-G) is a non-classical HLA class I molecule with an important role at the fetus-maternal interface, preventing fetus recognition and abortion. The role of HLA-G as an immune-modulatory and anti-inflammatory molecule has led to investigate its role in pathological conditions. In these years, HLA-G has been shown to have an important implication in inflammatory pathologies. The focus of this review is to up-date the scientific knowledge on the expression of HLA-G molecules in inflammatory conditions.
2012
Rizzo, Roberta; Bortolotti, Daria; Baricordi, Olavio; Fainardi, Enrico
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1691704
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