Array-based method for detection of Copy number variations in the HLA locus for the genetic determination of susceptibility of development of venous malformations in the extracranial segments of the cerebrospinal veins and kit thereof

This disclosure concerns a Array-based method for detection of Copy number variations in the HLA locus with application in THE diagnosi of genetic usceptibility of venous malformations in the extracranial segments of the cerebrospinal veins associated with multiple sclerosis” I validated in a wider patients’ population the present disclosure may concern a genetic method for the determination of the genotype-phenotype correlation of venous malformations associated with multiple sclerosis and the diagnosis of genetic susceptibility to this phenotype.