The lypopolysaccharide (LPS) of Salmonella typhi has been characterized by SDS-PAGE and immunoblotting with sera from typhoid patients; also, the reaction pattern of human IgM and IgG antibodies to various antigenic determinants of S. typhi LPS has been evaluated. All typhoid sera revealed the characteristic LPS profile. Immunoblot analysis has shown that patients with typhoid fever produce antibodies directed against various antigenic determinants located along the O-side chains as well as the core-lopid A region of S. typhi LPS. Thus IgM and IgG antibodies recognize common antigen determinants.
Valutazione della risposta immune di tipo IgM e IgG verso il lipopolisaccaride (LPS) di Salmonella typhi mediante SDS-PAGE ed Immnuoblotting.
CONTINI, Carlo;
1988
Abstract
The lypopolysaccharide (LPS) of Salmonella typhi has been characterized by SDS-PAGE and immunoblotting with sera from typhoid patients; also, the reaction pattern of human IgM and IgG antibodies to various antigenic determinants of S. typhi LPS has been evaluated. All typhoid sera revealed the characteristic LPS profile. Immunoblot analysis has shown that patients with typhoid fever produce antibodies directed against various antigenic determinants located along the O-side chains as well as the core-lopid A region of S. typhi LPS. Thus IgM and IgG antibodies recognize common antigen determinants.File in questo prodotto:
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