A sample of 1051 individuals from the Province of Ferrara in Italy was typed for the red-cell enzymes ESD, GPT and 6PGD; about 500 of these were also typed for DIA, GLO and PGP. The birthplace of the individuals in the sample, and the birthplace of their parents, were also obtained, and the interparental distance was calculated. In the sample studied, no correlation was found between interparental distance and the rate of heterozygosity at that distance; no correlation was observed between the rate of heterozygosity in an individual and his interparental distance; the significant correlations between the genetic distances existing between pairs of individuals and the distance between their birthplaces was significant but trivial. On the other hand, it was observed that in the same data, a significant correlation exists between genetic distances and geographic distances when the genetic indicators are computed according to the methods of Cavalli-Sforza and Morton. It was concluded that a significant correlation between these indicators and geographic distance is not necessarily indicative that there is a detectable increase of heterozygosity in the progeny with an increase of interparental distance. © 1983 Academic Press Inc. (London) Limited.
Heterozygosity and geographic distances in a limited area
BARRAI, Italo Enrico;BARBUJANI, Guido;BERETTA, Maria;
1983
Abstract
A sample of 1051 individuals from the Province of Ferrara in Italy was typed for the red-cell enzymes ESD, GPT and 6PGD; about 500 of these were also typed for DIA, GLO and PGP. The birthplace of the individuals in the sample, and the birthplace of their parents, were also obtained, and the interparental distance was calculated. In the sample studied, no correlation was found between interparental distance and the rate of heterozygosity at that distance; no correlation was observed between the rate of heterozygosity in an individual and his interparental distance; the significant correlations between the genetic distances existing between pairs of individuals and the distance between their birthplaces was significant but trivial. On the other hand, it was observed that in the same data, a significant correlation exists between genetic distances and geographic distances when the genetic indicators are computed according to the methods of Cavalli-Sforza and Morton. It was concluded that a significant correlation between these indicators and geographic distance is not necessarily indicative that there is a detectable increase of heterozygosity in the progeny with an increase of interparental distance. © 1983 Academic Press Inc. (London) Limited.I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
