In a study of the space distribution of eight red blood cells markers in European and Asian populations, evidence for a longitudinal cline of GLO, ESD, PGP, AK, and 6-PGD allele frequencies was found. The respective Fst values appeared significantly greater than those computed at loci whose allele frequencies are not associated with longitude, namely ADA, GPT, and SOD. A systematic pressure appears to have acted upon the former systems, even though the effects of selection can partially overlap with the effects of migratory movements, which have already been demonstrated in the studied area. Conversely, random genetic drift, or random fluctuation of selection coefficients, cannot account for the observed gene frequency diversity. © 1986 Academic Press Inc. (London) Limited.

Diversity of some gene frequencies in European and Asian populations. Effects of longitude

BARBUJANI, Guido;
1986

Abstract

In a study of the space distribution of eight red blood cells markers in European and Asian populations, evidence for a longitudinal cline of GLO, ESD, PGP, AK, and 6-PGD allele frequencies was found. The respective Fst values appeared significantly greater than those computed at loci whose allele frequencies are not associated with longitude, namely ADA, GPT, and SOD. A systematic pressure appears to have acted upon the former systems, even though the effects of selection can partially overlap with the effects of migratory movements, which have already been demonstrated in the studied area. Conversely, random genetic drift, or random fluctuation of selection coefficients, cannot account for the observed gene frequency diversity. © 1986 Academic Press Inc. (London) Limited.
1986
Barbujani, Guido; Milani, F.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1682417
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