PerioGlas is a synthetic absorbable osteoconductive bone graft substitute composed of a calcium phospho-silicate bioactive glass. To evaluate its effect on Adipose Drived Stem Cells colture, a gene expression analysis was carried out by using Reverse Transcriptase Polymerase Chain Reaction. The up-regulation of SPP1, FOSL1 and RUNX2, demonstrated that PerioGlass promotes osteoblast differentiation in ADSCs and is actively resorbed by human osteoclasts. For these reasons it could be used as scaffold in bone tissue engineering
PERIOGLASS AND ITS OSTEOGENIC POTENTIAL
CARINCI, Francesco;PALMIERI, Annalisa;SOLLAZZO, Vincenzo
2012
Abstract
PerioGlas is a synthetic absorbable osteoconductive bone graft substitute composed of a calcium phospho-silicate bioactive glass. To evaluate its effect on Adipose Drived Stem Cells colture, a gene expression analysis was carried out by using Reverse Transcriptase Polymerase Chain Reaction. The up-regulation of SPP1, FOSL1 and RUNX2, demonstrated that PerioGlass promotes osteoblast differentiation in ADSCs and is actively resorbed by human osteoclasts. For these reasons it could be used as scaffold in bone tissue engineeringFile in questo prodotto:
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