The aim of this study was a histological evaluation of skin lesions induced from the radiosurgical unit and voltaic arc dermoabrasion: a rabbit model. Materials and methods: eight New Zealand male rabbits with a weight average 3.9 Kg, participated in this study. Dorsal part of each rabbit was shaven and divided in two equal parts of 5 cm. Voltaic arc dermoabrasion ( Plexer, GMV s.r.l. Grottaferrata, Italy) in one side and radiosurgical unit (Laser elettronica Milano 1,75 MH) on the other were used to remove the keratinized layer. In each area were performed 10 sites of abrasion for a total of 20 sites per rabbit. The animals were sacrificed in groups of two at days: 0, 7, 14 and 21 with a Tanax overdose. The treated skin was removed using a scalpel and a block section containing the subcutaneous layer was effectuated. There were obtained 20 biopsies from each block section, 10 performed with el- bras and 10 with radiosurgical unit for a total of 40 biopsies per study time. Results: the present results demonstrated the possibility on containing the thermal damage of the lesions adjacent tissues using dermoabrasion. There were no observations of thermal damage on the underlying dermal tissue. Absent necrotic layer on the healing process was shown but an inflammatory infiltrate was present. The reduced thermal damage on the subcutaneous tissue is probably due to the current passage absence on the tissues. This is necessary to close the electric circuit between the active electrode and the neutral one in which the patient is part when using the radiosurgical unit. The arc voltaic dermoabrasion technique in comparison with the electroscalpel demonstrated the capability to contain the damage within the parenchyma

SKIN LESIONS INDUCED FROM THE RADIOSURGICAL UNIT AND VOLTAIC ARC DERMOABRASION: A RABBIT MODEL

CARINCI, Francesco;
2011

Abstract

The aim of this study was a histological evaluation of skin lesions induced from the radiosurgical unit and voltaic arc dermoabrasion: a rabbit model. Materials and methods: eight New Zealand male rabbits with a weight average 3.9 Kg, participated in this study. Dorsal part of each rabbit was shaven and divided in two equal parts of 5 cm. Voltaic arc dermoabrasion ( Plexer, GMV s.r.l. Grottaferrata, Italy) in one side and radiosurgical unit (Laser elettronica Milano 1,75 MH) on the other were used to remove the keratinized layer. In each area were performed 10 sites of abrasion for a total of 20 sites per rabbit. The animals were sacrificed in groups of two at days: 0, 7, 14 and 21 with a Tanax overdose. The treated skin was removed using a scalpel and a block section containing the subcutaneous layer was effectuated. There were obtained 20 biopsies from each block section, 10 performed with el- bras and 10 with radiosurgical unit for a total of 40 biopsies per study time. Results: the present results demonstrated the possibility on containing the thermal damage of the lesions adjacent tissues using dermoabrasion. There were no observations of thermal damage on the underlying dermal tissue. Absent necrotic layer on the healing process was shown but an inflammatory infiltrate was present. The reduced thermal damage on the subcutaneous tissue is probably due to the current passage absence on the tissues. This is necessary to close the electric circuit between the active electrode and the neutral one in which the patient is part when using the radiosurgical unit. The arc voltaic dermoabrasion technique in comparison with the electroscalpel demonstrated the capability to contain the damage within the parenchyma
2011
A., Scarano; Carinci, Francesco; B., Sinjari; L., Artese; G., Fippi; G., Brunelli; R., Monguzzi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1520319
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