A number of 40-aza-20,30-dideoxy nucleosides have been synthesized in good yields and short reaction times by straightforward microwave assisted 1,3-cycloaddition of vinyl nucleobases with nitrones, in the absence of solvent. The vinyl nucleobases are used, for the first time, in their unprotected form
Solvent-free, microwave assisted 1,3-cycloaddition of nitrones with vinyl nucleobases for the synthesis of N,O-nucleosides
BORTOLINI, Olga;
2008
Abstract
A number of 40-aza-20,30-dideoxy nucleosides have been synthesized in good yields and short reaction times by straightforward microwave assisted 1,3-cycloaddition of vinyl nucleobases with nitrones, in the absence of solvent. The vinyl nucleobases are used, for the first time, in their unprotected formFile in questo prodotto:
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