Four uremic patients with advanced peripheral arterial occlusive disease (PAOD) of lower limbs causing rest pain and ischemic-necrotic lesions were treated with a four-hour intravenous infusion of Iloprost at doses of 0.75- 2.5 ng/kg/min for twenty-eight days. After a week of the therapy all patients experienced disappearance of rest pain and prolonged walking distance. At the end of the trial a diabetic patient showed a complete regression of the necrotic areas of two toes while the other patients still showed ischemic- necrotic foot lesions that were well demarcated. Iloprost therapy can be effective in uremic patients with severe PAOD.

Favorable clinical effects of Iloprost infusion in 4 uremic patients with critical limb ischemia

FABBIAN, Fabio;
1992

Abstract

Four uremic patients with advanced peripheral arterial occlusive disease (PAOD) of lower limbs causing rest pain and ischemic-necrotic lesions were treated with a four-hour intravenous infusion of Iloprost at doses of 0.75- 2.5 ng/kg/min for twenty-eight days. After a week of the therapy all patients experienced disappearance of rest pain and prolonged walking distance. At the end of the trial a diabetic patient showed a complete regression of the necrotic areas of two toes while the other patients still showed ischemic- necrotic foot lesions that were well demarcated. Iloprost therapy can be effective in uremic patients with severe PAOD.
1992
Bedani, P. L.; Perini, L.; Farinelli, R.; Fabbian, Fabio; Fiocchi, O.; Guerra, S.; Vanini, A.; Gilli, P.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1400556
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