A versatile synthesis of 1,6-a-D-oligomannosides featuring the 1,4-disubstituted triazole ring as interglycosidic tether is presented via iterative copper(I)-catalyzed azide–alkyne cycloaddition. Free hydroxy hexamannoside and decamannoside featuring a capping 6-deoxymannose fragment have been prepared and characterized.
Studies Toward the Synthesis of Inhibitors of Mycobacterium tuberculosis Cell-Wall Biosynthesis: The Assembly of Triazole-Linked 1,6-alpha-D-Oligomannosides via Click CuAAC
LO CONTE, Mauro;MARRA, Alberto;DONDONI, Alessandro
2009
Abstract
A versatile synthesis of 1,6-a-D-oligomannosides featuring the 1,4-disubstituted triazole ring as interglycosidic tether is presented via iterative copper(I)-catalyzed azide–alkyne cycloaddition. Free hydroxy hexamannoside and decamannoside featuring a capping 6-deoxymannose fragment have been prepared and characterized.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in SFERA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
