A commercial reversed-phase (RP) C18 HPLC column has been dynamically coated with the chiral selector N<n-decyI-L-spinacine and then loaded with copper(ll) ions. Several racemic mixtures of underivatized amino acids and oligopeptides were resolved on the column by chiral ligand-exchange chromatography. The most important experimental conditions affecting column efficiency, retention, and selectivity (temperature and mobile phase flow rate and composition) were extensively investigated.

Chiral Ligand-Exchange Chromatography on a RP-HPLC Column Coated with a New Chiral Selector Derived from L-Spinacine

REMELLI, Maurizio;CONATO, Chiara
2002

Abstract

A commercial reversed-phase (RP) C18 HPLC column has been dynamically coated with the chiral selector N
Remelli, Maurizio; D., Trombin; Conato, Chiara
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1208084
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