The typical circadian pattern of blood pressure exhibits two daytime peaks: a prominent one around 0800–0900 h and a secondary one around 1900–2000 h. The two daytime peaks are still present when a siesta effect is excluded or the patients are not Italian. Since increased blood pressure levels are a predisposing factor for aortic dissection, it seems possible to maintain that both circadian blood pressure peaks may be crucial in determining rupture of a critically weakened aortic wall, while it is also possible that many other factors that show a similar circadian variation may contribute to the determination of the circadian pattern of aortic rupture.
Circadian variation in thrombotic risk factors in haemorrhagic cardiovascular events - Reply
MANFREDINI, Roberto;PORTALUPPI, Francesco
1999
Abstract
The typical circadian pattern of blood pressure exhibits two daytime peaks: a prominent one around 0800–0900 h and a secondary one around 1900–2000 h. The two daytime peaks are still present when a siesta effect is excluded or the patients are not Italian. Since increased blood pressure levels are a predisposing factor for aortic dissection, it seems possible to maintain that both circadian blood pressure peaks may be crucial in determining rupture of a critically weakened aortic wall, while it is also possible that many other factors that show a similar circadian variation may contribute to the determination of the circadian pattern of aortic rupture.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
