Wittig reaction of 4-[(4-methylphenyl)sulfonyl]-1-(triphenylphosphoranylidene)butan-2-one with N-protected alpha-amino aldehydes furnished N-protected gamma-amino-alpha,beta-unsaturated keto sulfones which have been conveniently utilized as precursors of both aromatic and non-aromatic 2,5-disubstituted five-membered heterocyclic compounds.
Synthesis of 2,5-disubstituted pyrroles and pyrrolidines by intramolecular cyclization of 6-amino-3-keto sulfones
BENETTI, Simonetta;DE RISI, Carmela;MARCHETTI, Paolo;POLLINI, Gian Piero;ZANIRATO, Vinicio
2002
Abstract
Wittig reaction of 4-[(4-methylphenyl)sulfonyl]-1-(triphenylphosphoranylidene)butan-2-one with N-protected alpha-amino aldehydes furnished N-protected gamma-amino-alpha,beta-unsaturated keto sulfones which have been conveniently utilized as precursors of both aromatic and non-aromatic 2,5-disubstituted five-membered heterocyclic compounds.File in questo prodotto:
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