The geometrical features of the proposed bioactive conformation of peptide T assessed by computational methods in a previous study, together with available structure-activity studies on peptide T, led us to propose a pharmacophore for the CD4-peptide T interaction. Subsequent, data base searching permitted us to identify amygdalin as a peptide T peptidomimetic.

Amygdalin binds to the CD4 receptor as suggested from molecular modeling studies

MARASTONI, Mauro;
1998

Abstract

The geometrical features of the proposed bioactive conformation of peptide T assessed by computational methods in a previous study, together with available structure-activity studies on peptide T, led us to propose a pharmacophore for the CD4-peptide T interaction. Subsequent, data base searching permitted us to identify amygdalin as a peptide T peptidomimetic.
Llorens, O; Filizola, M; Spisani, S; Marastoni, Mauro; Herranz, C; Perez, Jj
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1205808
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