A digital autoradiography system based on double sided silicon strip detectors (1.6 × 1.6 mm2 active surface with 100 μm pitch) has been developed and successfully tested with beta-emitting tracers. It is shown here that the system is able to perform imaging of organic material with specific sensitivity as small as 0.002 nCi/mm2, and to record activity measurements with good linearity in the range 0.002-20nCi/mm2. Autoradiographic images of clusters of mammary cells marked with ortho-(32P)phosphate, obtained with an exposure time of about 10 min are presented.
Autoradiography with silicon strip detectors
GAMBACCINI, Mauro;MARZIANI, Michele;TAIBI, Angelo;TRIPICCIONE, Raffaele;
1996
Abstract
A digital autoradiography system based on double sided silicon strip detectors (1.6 × 1.6 mm2 active surface with 100 μm pitch) has been developed and successfully tested with beta-emitting tracers. It is shown here that the system is able to perform imaging of organic material with specific sensitivity as small as 0.002 nCi/mm2, and to record activity measurements with good linearity in the range 0.002-20nCi/mm2. Autoradiographic images of clusters of mammary cells marked with ortho-(32P)phosphate, obtained with an exposure time of about 10 min are presented.File in questo prodotto:
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