Two- and three-component Hantzsch-type cyclocondensation reactions were carried out under thermal conditions using C-glycosylated reagents, namely sugar aldehydes, ketoesters, and enamines. Two different series of 1,4-dihydropyridines bearing C-glycosyl moieties at C4 and C6 were obtained in good to excellent overall yields (61-90%). The asymmetric induction due to carbohydrate residues was also investigated.

Two- and three-component Hantzsch reaction using C-glycosylated reagents. Approach to the asymmetric synthesis of 1,4-diyhydropyridines

DONDONI, Alessandro;MASSI, Alessandro;
2002

Abstract

Two- and three-component Hantzsch-type cyclocondensation reactions were carried out under thermal conditions using C-glycosylated reagents, namely sugar aldehydes, ketoesters, and enamines. Two different series of 1,4-dihydropyridines bearing C-glycosyl moieties at C4 and C6 were obtained in good to excellent overall yields (61-90%). The asymmetric induction due to carbohydrate residues was also investigated.
2002
Dondoni, Alessandro; Massi, Alessandro; Minghini, E.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1201417
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