We have used the EGS4 Monte Carlo code of W.R. Nelson et al. (1985) to simulate the performance of a positron emission tomograph (PET) for small animals. The PET scanner is a four-head detector, made of matrices of 400 YAP:Ce (yttrium aluminium perovskite doped with cerium) finger-like crystals (2×2×30 mm3 each), coupled to Hamamatsu R2486-06 position-sensitive photomultipliers. 3D reconstruction algorithms have been applied to the 3D simulated data. The reconstructed volume was 2×2×2 cm3, the same as that of the reference mouse brain. The Monte Carlo results show that a spatial resolution below 2 mm (FWHM) can be obtained over the 2×2×2 cm3 volume with a sensitivity of about 600 counts/(μCis) for a gantry diameter of 15 cm and a threshold of 50 keV

A 3-D Monte Carlo simulation of a small animal Positron Emission Tomograph with millimeter spatial resolution

DEL GUERRA, Alberto;DI DOMENICO, Giovanni;SCANDOLA, Maddalena;ZAVATTINI, Guido
1999

Abstract

We have used the EGS4 Monte Carlo code of W.R. Nelson et al. (1985) to simulate the performance of a positron emission tomograph (PET) for small animals. The PET scanner is a four-head detector, made of matrices of 400 YAP:Ce (yttrium aluminium perovskite doped with cerium) finger-like crystals (2×2×30 mm3 each), coupled to Hamamatsu R2486-06 position-sensitive photomultipliers. 3D reconstruction algorithms have been applied to the 3D simulated data. The reconstructed volume was 2×2×2 cm3, the same as that of the reference mouse brain. The Monte Carlo results show that a spatial resolution below 2 mm (FWHM) can be obtained over the 2×2×2 cm3 volume with a sensitivity of about 600 counts/(μCis) for a gantry diameter of 15 cm and a threshold of 50 keV
Bevilacqua, A; Bollini, D; DEL GUERRA, Alberto; DI DOMENICO, Giovanni; Galli, M; Scandola, Maddalena; Zavattini, Guido
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1200873
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