N-formyl- and N-acetyl-peptides were synthesized and compared in order to understand which features can best elicit biological responses. The behavior of N-formyl-peptides confirms the previously found sequential obligations in the residues, while acetyl-derivatives do not seem suitable for an efficacious stimulation of human neutrophils.

Differences arising in human neutrophil activation passing from N-formyl to N-acetyl-oligopeptides

Spisani S.;Cavicchioni G.
2000

Abstract

N-formyl- and N-acetyl-peptides were synthesized and compared in order to understand which features can best elicit biological responses. The behavior of N-formyl-peptides confirms the previously found sequential obligations in the residues, while acetyl-derivatives do not seem suitable for an efficacious stimulation of human neutrophils.
2000
Spisani, S.; Cavicchioni, G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1200624
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