Studies of the association between HHV-6 and multiple sclerosis are hindered by the difficulty in discriminating between latent and active infection. A follow up study was undertaken of patients with multiple sclerosis, searching peripheral blood mononuclear cells for molecular markers associated with HHV-6 latency and lytic replication. The results show that HHV-6 is latent and did not support systemic infection in patients with multiple sclerosis. Likewise, patients with multiple sclerosis did not show any evidence of active infection with other human herpesviruses HHV-7 and HHV-8.

Human herpesvirus 6 is latent in peripheral blood of patients with relapsing-remitting multiple sclerosis

ROTOLA, Antonella;CASSAI, Enzo;GRANIERI, Enrico Gavino Giuseppe;DI LUCA, Dario
1999

Abstract

Studies of the association between HHV-6 and multiple sclerosis are hindered by the difficulty in discriminating between latent and active infection. A follow up study was undertaken of patients with multiple sclerosis, searching peripheral blood mononuclear cells for molecular markers associated with HHV-6 latency and lytic replication. The results show that HHV-6 is latent and did not support systemic infection in patients with multiple sclerosis. Likewise, patients with multiple sclerosis did not show any evidence of active infection with other human herpesviruses HHV-7 and HHV-8.
1999
Rotola, Antonella; Cassai, Enzo; Tola, Mr; Granieri, Enrico Gavino Giuseppe; DI LUCA, Dario
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11392/1200433
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